Molecular Mechanisms Underlying Environmental Enrichment-Induced Neuroprotection in Vulnerability to Nicotine Addiction
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[Nicotine and animal models: what does the environmental enrichment paradigm tell us?].
The Environmental Enrichment (EE) paradigm is a housing condition which aims is to provide physical, cognitive and sensorial stimulation to rodents. Animals are housed in larger cages containing inanimate objects such as tunnels, toys and running wheels. The main aim of the current work is to tackle the arguments which suggest that EE may diminish vulnerability to developing addiction to nicoti...
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Nicotine is the addictive substance in tobacco and it has a broad impact on both the central and peripheral nervous systems. Over the past decades, an increasing number of genes potentially involved in nicotine addiction have been identified by different technical approaches. However, the molecular mechanisms underlying nicotine addiction remain largely unclear. Under such situation, a comprehe...
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تاریخ انتشار 2015